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        • Type of Molecule (Tx)
        • Small Molecules
        • Biologics

         

        • Target Indication (Tx+Dx)
        • Acne Vulgaris
        • Atopic Dermatitis
        • Clostridium difficile Infection
        • Colorectal Cancer
        • Crohn’s Disease
        • Diabetes
        • Irritable Bowel Syndrome
        • Lactose Intolerance
        • Lung Cancer
        • Nonalcoholic steatohepatitis (NASH)
        • Obesity
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        • Therapeutic Area (Tx+Dx)
        • Autoimmune Disorders
        • Dental Disorders
        • Digestive and Gastrointestinal Disorders
        • Dermatological Disorders
        • Infectious Disease
        • Metabolic Disorders
        • Oncology
        • Others

         

        • Key Geographical Regions (Tx+Dx)
        • North America
        • Europe
        • Asia-Pacific and Rest of the World

         

         

        The Human Microbiome Market, 2019-2030 report features the following companies, which we identified to be key players in this domain:

        • 4D Pharma
        • Armata Pharmaceuticals
        • Evelo Biosciences
        • Rebiotix (Acquired by Ferring Pharmaceuticals)
        • Seres Therapeutics
        • Vedanta Biosciences

         

        Table of Contents

        1. Preface

         

        1. Executive Summary

         

        1. Introduction

         

        1. Microbiome Therapeutics: Market Landscape

         

        1. Company and Drug Profiles

         

        1. Microbiome Diagnostics: Market Landscape

         

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        1. Attractiveness Competitiveness (AC) Matrix

         

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        1. Start-up Health Indexing

         

        1. Key Therapeutics Areas

         

        1. Funding and Investment Analysis

         

        1. Contract Services for Microbiome Therapeutics

         

        1. Big Data and Microbiome Therapeutics

         

        1. Microbiome Therapeutics: Market Forecast and Opportunity Analysis

         

        1. Microbiome Diagnostics: Market Forecast and Opportunity Analysis

         

        1. Fecal Microbiota Therapies: Market Forecast and Opportunity Analysis

         

        1. Case Study: Microbiome-based Products in Other Industries

         

        1. Concluding Remarks

         

        1. Executive Insights

         

        1. Appendix I: Tabulated Data

         

        1. Appendix II: List of Companies and Organizations

         

         

        To purchase a copy, please visit https://www.rootsanalysis.com/reports/view_document/human-microbiome-market/281.html

         

        Contact Details

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        • Others

         

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        • VA
        • Hydrazone
        • Others

         

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        • Ovarian cancer
        • Others

         

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        • Others

         

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        • Europe
        • Asia Pacific

         

        The Antibody Drug Conjugates Market (5th Edition), 2019-2030.”  report features the following companies, which we identified to be key players in this domain:

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        • GlaxoSmithKline
        • Incyte
        • Novartis
        • Trillium Therapeutics

         

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        To purchase a copy, please visit https://www.rootsanalysis.com/reports/view_document/antibody-drug-conjugates-market-5th-edition-2019-2030/270.html

         

        Contact Details

        Gaurav Chaudhary

        +1 (415) 800 3415

        gaurav.chaudhary@rootsanalysis.com  

         

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        Industry and non-industry playersclaim to have the necessary expertise and supporting infrastructure to manufacture - Roots Analysis


        Submitted 3 day(s) ago by Alberto Brando

         

         

        The production of radiopharmaceuticals as compared to traditional pharmaceuticals is a multifaceted procedure and requires specialized facilities, equipment and operational expertise. Further, owing to its inherent hazardous nature, radiopharmaceuticals have a complex regulatory market authorization process. Consequently, a number of innovator companies have demonstrated a preference for outsourcing radiopharmaceutical manufacturing to contract service providers.

         

        To order this 320+ page report, which features 45+ figures and 100+ tables, please visit this - https://www.rootsanalysis.com/reports/nuclear-medicine-and-radiopharmaceuitcals-manufacturing.html

         

        The USD 6+ billion (by 2030) financial opportunity associated with nuclear medicine and radiopharmaceuticals manufacturing, has been analyzed across the following segments:

        • Target Disease Indication 
        • Breast Cancer
        • Chronic Lymphocytic Leukemia
        • Colorectal Cancer
        • Head and Neck Cancer
        • Lung Cancer
        • Lupus Nephritis
        • Melanoma
        • Multiple Myeloma
        • Primary Sjögren's Syndrome
        • Others 

         

        • Target Immune Checkpoint
        • B7-H3
        • CD38
        • CD40
        • CD47
        • Others

         

        • Mechanism of Action
        • Inhibitory
        • Stimulatory

         

        • Therapeutic Modality
        • Monoclonal Antibody
        • Small Molecule

         

        • Type of Therapy 
        • Monotherapy 
        • Combination Therapy

         

        • Route of Administration
        • Intravenous
        • Subcutaneous
        • Others

         

        • Key Geographical Regions 
        • North America
        • Europe
        • Asia-Pacific and the Rest of the World 

         

        The Nuclear Medicine and Radiopharmaceuticals Manufacturing Market, 2020-2030” report features the following companies, which we identified to be key players in this domain:

        • Advanced Accelerator Applications
        • Belgian Nuclear Research Center (SCK•CEN)
        • Cardinal Health
        • China Isotope & Radiation Corporation
        • Curium Pharma
        • DuChemBio
        • Eckert & Ziegler
        • Eczacibasi-Monrol
        • GE Healthcare
        • Jubilant DraxImage
        • Lantheus Medical Imaging
        • Nihon Medi-Physics
        • Nordion
        • PETNET Solutions
        • SinoTau Pharmaceuticals
        • SOFIE

         

         

        To purchase a copy, please visit https://www.rootsanalysis.com/reports/nuclear-medicine-and-radiopharmaceuitcals-manufacturing.html

         

        Contact Details

        Gaurav Chaudhary

        +1 (415) 800 3415

        gaurav.chaudhary@rootsanalysis.com  

         

        The nuclear medicine and radiopharmaceuticals manufacturing market is projected to grow - Roots Analysis


        Submitted 3 day(s) ago by Alberto Brando

         

        Roots Analysis has announced the addition of “Nuclear Medicine and Radiopharmaceuticals Manufacturing Market, 2020-2030” report to its list of offerings.

         

        To order this 320+ page report, which features 45+ figures and 100+ tables, please visit this link

         

        Key Market Insights

        • Close to 130 industry and non-industry players, across the globe, claim to have the necessary expertise and supporting infrastructure to manufacture a wide variety of radioisotopes, for in-house use, or as a contract service
        • The market is fragmented, featuring the presence of companies in both developed and developing nations, which are capable of manufacturing radiopharmaceuticals for various applications at different scales of production
        • The growing interest in this field is reflected in the yearly growth in partnership activity; the majority of deals inked in the recent past include manufacturing and supply agreements for various types of radiopharmaceuticals
        • Stakeholders are actively expanding their capabilities in order to enhance their respective nuclear medicine and radiopharmaceutical manufacturing capabilities and, thereby, maintain a competitive edge in this industry
        • Case Study: The decay product of Mo-99, Tc-99m, is used in majority of the radioactivity-based diagnostic applications in the US; reactors in the European region alone contribute to 60% of the global production capacity
        • In the long-term, the forecasted opportunity is anticipated to be higher for radioisotopes intended for diagnostic applications, mostly for use in the field of cardiology, with North America holding the dominant position
        • SPECT and beta-emitters are anticipated to generate the majority share of revenues across diagnostic and therapeutic applications, respectively, for both in-house use and radiopharmaceutical supply contracts

         

        For more information, please visit https://www.rootsanalysis.com/reports/nuclear-medicine-and-radiopharmaceuitcals-manufacturing.html

        Contact Details

        Gaurav Chaudhary

        +1 (415) 800 3415

        gaurav.chaudhary@rootsanalysis.com

        Over 115 companies located in various regions across the globe claim to provide contract fill / finish services - Roots Analysis


        Submitted 3 day(s) ago by Alberto Brando

         

        Despite the fact that biopharmaceuticals offer significant profit margins, innovator companies are plagued by high costs of development, complex production protocols and special procedures and equipment for fill / finish operations. Consequently, a number of drug manufacturers have demonstrated a preference for outsourcing fill / finish operations of such products.

         

        To order this 480+ page report, which features 350+ figures and 260+ tables, please visit this - https://www.rootsanalysis.com/reports/view_document/biologics-fill--finish-services-market-2019-2030/256.html

         

        The USD 4.2 billion (by 2030) financial opportunity within the biologics fill / finish services market has been analyzed across the following segments:

        • Types of Primary Packaging Containers
        • Ampoules
        • Cartridges
        • Syringes
        • Vials

         

        • Types of Biologics
        • Peptides / proteins
        • Antibodies
        • Vaccines
        • Cell therapies
        • Gene therapies
        • Viral products
        • Oligonucleotides
        • Others

         

        • Company Size
        • Small-sized
        • Mid-sized
        • Large / very large

         

        • Scale of Operation
        • Preclinical
        • Clinical
        • Commercial

         

        • Key Therapeutic Areas
        • Cancer
        • Infectious diseases
        • Autoimmune diseases
        • Cardiovascular diseases
        • Other indications

         

        • Key Geographical Regions
        • North America (US, Canada)
        • Europe (UK, France, Germany, Italy, Spain and rest of the Europe)
        • Asia-Pacific (Japan, China, South Korea, India and Australia)

         

        The Biologics Fill / Finish Services Market, 2019-2030.”report features the following companies, which we identified to be key players in this domain:

        • Advanced BioScience Laboratories (ABL)
        • Albany Molecular Research (AMRI)
        • Biocon
        • BioPharma Solutions
        • BioReliance
        • Boehringer Ingelheim BioXcellence
        • ChemPartner
        • Emergent BioSolutions
        • IDT Biologika
        • Lonza
        • LuinaBio
        • Mycenax Biotech
        • Patheon
        • Recipharm
        • Vetter Pharma
        • WuXi Biologics

         

        Table of Contents

         

        1. Preface

          2. Executive Summary

        2. Introduction

        3. Competitive Landscape

        4. Company Competitiveness Analysis

        5. Biologics Fill / Finish Service Providers in North America: Company Profiles

        6. Biologics Fill / Finish Service Providers in Europe: Company Profiles

        7. Biologics Fill / Finish Service Providers in Asia-Pacific: Company Profiles

        8. Partnerships and Collaborations

        9. Recent Expansions

        10. Capacity Analysis

        11. Demand Analysis

        12. Biologics Manufacturing and Fill / Finish: Key Performance Indicator Analysis

        13. Market Sizing and Opportunity Analysis

         

        1. Future Growth Opportunities

         

        1. Case Study: Robotic Systems in Fill / Finish Operations

         

        1. Case Study: Ready-to-Use Packaging Components in Aseptic Fill / Finish Operations

         

        1. Conclusion

         

        1. Interview Transcripts

         

        1. Appendix 1: Tabulated Data

         

        1. Appendix 2: List of Companies and Organizations

         

        To purchase a copy, please visit https://www.rootsanalysis.com/reports/view_document/biologics-fill--finish-services-market-2019-2030/256.html

         

        Contact Details

        Gaurav Chaudhary

        +1 (415) 800 3415

        gaurav.chaudhary@rootsanalysis.com  

         

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          Why you should not reuse cooking oil?

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          Submitted 5 day(s) ago by sherlysylvia

           

          Researchers from the University of the Basque Country (UPV / EHU) have discovered for the first time in food the presence of certain aldehydes suspected of being behind neurodegenerative diseases and some types of cancer. These toxic compounds appear in some oils when heated to frying temperature and even more so when reused. Reheating oils isn't really healthy, and here's what you need to know about it.

          Heating and reheating oils at frying temperature creates toxic compounds

          If you're like most people, you probably reuse your frying oil many times. After all, it can be expensive and it may seem pointless to throw it away.

          However, reheating oils poses health risks. How many times you can safely reuse it will depend on what type of oil it is, at what temperature it was heated, and for how long.

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          The study

          According to the University of the Basque Country, the work confirms the simultaneous presence in the frying oil of several toxic aldehydes from the group of α, β unsaturated oxygenates, such as 4-hydroxy- [E] -2nonenal.

          Furthermore, two of them are described for the first time in foods (4-oxo- [E] -2-decenal and 4-oxo- [E] -2-undecenal). Until now, these substances had only been cited in biomedical studies, where their existence in the body is related to various types of cancer and neurodegenerative diseases, such as Alzheimer's and Parkinson's.

          Toxic aldehydes are generated as a result of the degradation of fatty acids in the oil and, although some are volatile, others remain in the oil after frying. This way, if you tend to reheat oils, they can be incorporated into cooked food. As they are very reactive compounds, they can react with proteins, hormones and enzymes in the body and prevent their proper functioning.

          Health risks of reheating cooking oils

          Toxic fumes

          An oil heated to high temperatures releases toxic fumes. The fumes are emitted even before the smoke point is reached, but increase dramatically when the temperature exceeds the smoke point.

          One study found that canola oil, which has a high smoke point, emitted the lowest level of toxic fumes. Coconut oil gave off the most smoke and at the lowest temperature. Extra virgin olive oil and safflower oil were in the middle.

          Another experiment, published in the Food Chemistry magazine, consisted of heating three types of oil to 190 ºC in an industrial fryer: olive, sunflower and flax. The operation was carried out for 40 hours (8 hours a day) in the first two and in 20 hours in the case of flax oil. The latter is not commonly used for cooking in the West, but has been selected for its high content of omega 3 groups.

          The results reveal that sunflower and flax oils –especially the first one– are the ones that generate the greatest number of toxic aldehydes and in less time. On the contrary, olive oil, which has a higher concentration of monounsaturated acids (such as oleic), generates less and later these harmful compounds.

          Free radicals

          The free radicals are also produced when an oil reaches its smoke point. These are molecules that damage cells in our body and can potentially cause cancer.

          They are absorbed in foods that are fried and then can cause cancer or other illnesses in people who eat those foods.

          Trans fat

          Trans fats are "bad" fats that increase the risk of heart disease. At high temperatures, some of the fats in the oil turn into trans fats. When oils are reused, the amount of trans fat increases even more.

          A study that looked at olive and peanut oils found that trans fats increased significantly in both when they were reheated.

          HNE

          As mentioned above, HNE (4-hydroxy-2-trans-nonenal) is a toxic substance that can increase the risk of Alzheimer's, Parkinson's, stroke, and LDL (“bad”) cholesterol. Heating oil at 190 ° C or above causes HNE to form. While using oil only causes HNE to form, reusing it will cause even more HNE to build up.

          How to know when it's time to change your cooking oil

          By now you may be thinking: “But I've always reused the oil! Can I really use it only once? "

          The safest thing is to use new oil each time. However, there are some things you can do to limit the risks of reusing it.

          • If the oil looks cloudy, foams, or tastes or smells bad, it's time to throw it out.
          • If it's still fine and you plan to reuse it, filter the oil through a few layers of cheesecloth to remove any food particles before storing. Store the oil in a sealed, light-proof container, and keep it in the refrigerator if possible. Storing it in a cool, dark place is the next best option.
          • Don't mix different types of oil together.
          • Fry foods that do not exceed 190 C. Use a thermometer to check the temperature.
          • Shake off excess batter from food before frying to limit food particles left in the oil.
          • Choose stainless steel pots or pans for frying. Avoid iron or copper, as these will damage the oil more quickly.
          • Finally, turn off the heat right after you've finished cooking. The longer the oil is heated, the faster it will damage.
          • Even if the oil still seems fine, experts recommend discarding it after 3 months.

          Choosing the healthiest oil for frying

          While it may seem logical that healthier oils, such as olive oil, are the best options for frying, this is not always the case.

          The healthiest oil to use will depend on the temperature you are going to use.

          Each oil has its own approximate smoke point:

          • Unrefined palm oil at 235ºC
          • Safflower, peanut and soybean oil at 232ºC
          • Canola at 224ºC
          • Corn, Olive, Sesame and Sunflower at 210ºC

          When an oil is heated above its smoke point, toxins increase considerably. Therefore, the choice of which oil to use must take into account both the health of the oil itself and the temperature that will be used.

          For example, while olive oil is healthy at lower temperatures, if you are frying food above 210 C, it would not be a good option.

          Palm, peanut, safflower, or soybean oils can be safely heated to the highest temperatures. However, these oils contain a large amount of unhealthy saturated fat.

          Canola oil may be the best option in many cases. It contains the most unsaturated fats of any oil (even more than olive oil) and has a higher smoke point than olive oil. Also, it is generally much less expensive than olive oil.

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          Presently, close to 140 companies claim to be actively engaged in offering patient recruitment / retention services to the pharmaceutical and medical devices industries


          Submitted 6 day(s) ago by Alberto Brando

           

          A steadily increasing demand for study participants and the complexities associated with patient enrollment has imposed a significant burden on drug developer companies, prompting them to enlist the services of specialty service providers. Presently, close to 140 companies are actively offering patient recruitment and retention services. Majority of these players possess vast service portfolios and utilize diverse patient outreach methods to recruit study participants across different geographies and therapeutic indications.

           

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          The USD 5.3 billion (by 2030) financial opportunity within the patient recruitment and retention services market has been analyzed across the following segments:

          • Therapeutic Area
            • Oncology
            • Infectious Diseases
            • Cardiovascular Diseases
            • CNS Disorders
            • Respiratory Disorders
            • Metabolic Disorders
            • Others

           

          • Steps in Patient Recruitment Process
            • Pre-screening
            • Screening

           

          • Phase of Development
            • Phase I
            • Phase II
            • Phase III
            • Phase IV

           

          • Key Geographical Region 
            • North America
            • Europe
            • Asia-Pacific
            • Rest of the world

           

          The Patient Recruitment and Retention Services Marker, 2019-2030.report features the following companies, which we identified to be key players in this domain:

          • Acurian
          • BBK Worldwide
          • Bright Pharmaceuticals Services
          • ClinEdge
          • CSSi
          • CTM
          • FIDELIS RESEARCH
          • Ignite Data
          • Integrated Clinical Trial Services
          • MMG
          • Pacific Groove
          • Polaris BioPharma Consulting
          • Topstone Research
          • TrialWire
          • Tudor Reilly Health
          • WCCT Global

           

          Table of Contents

           

          1. Preface 
             
            2. Executive Summary
             
            3. Patient Recruitment and Retention In Clinical Trials
               
            4. Patient Outreach Methods
                
            5. Competitive Market Landscape of Patient Recruitment and Retention Service Providers
               
            6. Company Competitiveness Analysis

            7. Company Profiles

            8. Partnerships and Collaborations

            9. Recent Trends in Patient Recruitment and Retention
               
            10. Future Growth Opportunities 
             
            11. Market Sizing and Opportunity Analysis
             
            12. Conclusion 
               
            13. Interview Transcripts  
               
            14. Appendix 1: Tabulated Data
               
            15. Appendix 2: List of Companies and Organizations

           

          For more information, please visit https://www.rootsanalysis.com/reports/view_document/patient-recruitment-and-retention-services-market-2019-2030/245.html

           

          Contact Details

          Gaurav Chaudhary

          +1 (415) 800 3415

          gaurav.chaudhary@rootsanalysis.com  

           

          The patient recruitment and retention services market - Roots Analysis


          Submitted 6 day(s) ago by Alberto Brando

           

          A steadily increasing demand for participants in clinical research studies, coupled to the complexities associated with patient enrolment, have prompted drug / therapy developers to outsource this process to specialty service providers

           

          Roots Analysis  is pleased to announce the publication of its recent study, titled, “Patient Recruitment and Retention Services Marker, 2019-2030.

           

          The report offers a comprehensive study of the current scenario and future potential of the players providing patient enrollment and retention services. The study features an in-depth analysis, highlighting the capabilities of the various stakeholders in this domain. In addition to other elements, the study includes:

          • A detailed assessment of the current market landscape of companies offering patient recruitment and retention services.
          • An analysis of the most active regions (in terms of patient recruitment activity) engaged in this domain, featuring schematic world map representations that highlight key hubs across the globe.
          • An insightful 2X2 representation of the results of a competitiveness analysis of various service providers highlighting capable players in this domain, based on their respective capabilities.
          • Comprehensive profiles of patient recruitment and retention service providers (shortlisted on the basis of the number of services).
          • An analysis of the partnerships that have been established in this domain, in the recent past
          • A review of emerging trends in the industry to overcome the challenges associated with patient recruitment and retention
          • A detailed market forecast, featuring analysis of the current and projected future opportunity across key market segments (listed below)
          • Therapeutic Area
            • Oncology
            • Infectious Diseases
            • Cardiovascular Diseases
            • CNS Disorders
            • Respiratory Disorders
            • Metabolic Disorders
            • Others

           

          • Steps in Patient Recruitment Process
            • Pre-screening
            • Screening

           

          • Phase of Development
            • Phase I
            • Phase II
            • Phase III
            • Phase IV

           

          • Key Geographical Region 
            • North America
            • Europe
            • Asia-Pacific
            • Rest of the world

           

          Transcripts of interviews held with the following senior level representatives of stakeholder companies

          • Simon Klaasen, Co-founder and Managing Director, Link2Trials 
          • Hagit Nof, Chief Operation Officer and Business Development Officer, nRollmed
          • Paul Ivsin, Managing Director, Seeker Health 

           

          Key companies covered in the report

          • Acurian
          • BBK Worldwide
          • Bright Pharmaceuticals Services
          • ClinEdge
          • CSSi
          • CTM
          • FIDELIS RESEARCH
          • Ignite Data
          • Integrated Clinical Trial Services
          • MMG
          • Pacific Groove
          • Polaris BioPharma Consulting
          • Topstone Research
          • TrialWire
          • Tudor Reilly Health
          • WCCT Global

           

          For more information please click on the following link:

          https://www.rootsanalysis.com/reports/view_document/patient-recruitment-and-retention-services-market-2019-2030/245.html

           

          About Roots Analysis

          Roots Analysis is one of the fastest growing market research companies, sharing fresh and independent perspectives in the bio-pharmaceutical industry. The in-depth research, analysis and insights are driven by an experienced leadership team which has gained many years of significant experience in this sector. If you’d like help with your growing business needs, get in touch at info@rootsanalysis.com

           

          Contact Information

          Roots Analysis Private Limited

          Gaurav Chaudhary

          +1 (415) 800 3415

          gaurav.chaudhary@rootsanalysis.com

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